Speaker
Description
Affinity sensors are important diagnostics tools used for various biomedical applications. Various technologies are used for the development of biosensors. In some particular cases conducting polymers can be applied for the modification of surfaces used in biological recognition parts of biosensors. Recently conducting polymers are synthesized by several different methods: electrochemical [1], chemical [2], and biochemical [3-4]. Electrochemically generated conducting polymer based layers are frequently applied in the design of various types of electrochemical molecularly imprinted polymer based sensors for protein determination [5,6]. The incorporation of proteins, which is flowed by the extraction of these proteins from conducting polymer matrix [7], is a very important issue during the development of molecularly imprinted polymer based sensors. The applicability of electrochemically generated polymers in the design of various electrochemical affinity sensors [1] including molecularly imprinted polymers based sensors [5,6] will be discussed during the presentation.
References
1. A. Ramanavicius, et al. Electrochemical Formation of Polypyrrole-based Layer for Immunosensor Design. Sens Actuat B 2014, 197, 237. DOI: 10.1016/j.snb.2014.02.072
2. K. Leonavicius, et al. Polymerization Model for Hydrogen Peroxide Initiated Synthesis of Polypyrrole Nanoparticles. Langmuir 2011, 17, 10970. DOI:10.1021/la201962a
3. A. Ramanavicius, et al. Self-encapsulation of oxidases as a basic approach to tune upper detection limit of amperometric bosensors. Analyst 2008, 133, 1083. DOI:10.1039/b801501e
4. A. Ramanavicius, et al. Synthesis of Polypyrrole Within the Cell Wall of Yeast by Redox-Cycling of [Fe(CN)6]3-/[Fe(CN)6]4-. Enzyme Microb Technol 2016, 83, 40. DOI: 10.1016/j.enzmictec.2015.11.009
5. V. Liustrovaite, et al. Detection of the SARS-CoV-2 Nucleoprotein by Electrochemical Biosensor based on Self-Assembled Monolayer Supported Molecularly Imprinted Polypyrrole Formed on Gold Nanoparticle Modified Screen-Printed Electrode. Biosensors and Bioelectronics, 2025, 272, 17092. DOI:10.1016/j.bios.2024.117092 h
6. M. Drobysh, Molecularly imprinted composite-based biosensor for the determination of SARS-CoV-2 nucleocapsid protein. Biosensors and Bioelectronics, 2024, 251, 116043. DOI:10.1016/j.bios.2024.116043
7. E. Brazys, et al. Formation of molecularly imprinted polymers: strategies applied for the removal of protein template (Review). Advances in Colloid and Interface Science, 2025, 337, 103386 DOI:10.1016/j.cis.2024.103386
