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Abstract
Glucose is a vital energy source for cellular functions in living organisms, making it crucial to regulate its concentration within a healthy range in the bloodstream. Elevated glucose levels can cause extensive tissue damage, impacting organs such as the heart, eyes, kidneys, and nerves, potentially leading to severe and life-threatening complications. Currently, glucose biosensors constitute over 85% of the biosensor market, with electrochemical biosensors being particularly effective for glucose detection [1]. The integration of nanomaterials into electrochemical biosensors has been shown to enhance their analytical capabilities significantly. MXenes exhibit exceptional potential due to their high surface area, superior electrical conductivity, and hydrophilic nature, making them well-suited for biosensing applications [2].
This study explores the use of Ti₃C₂Tₓ MXenes in the development of a glucose biosensor. MXenes and glucose oxidase deposition on the electrode surface was optimized, and different electron transfer mediators were evaluated. The biosensor's analytical performance was then assessed through key performance parameters.
Keywords: Glucose, MXenes, Glucose oxidase
Acknowledgments: This project has received funding from EU Horizon Europe research program project # 101131147 “ESCULAPE”.
References
[1] A. Popov, et al., Sensors 2021, 21(3), 948.
[2] S. Adomaviciute-Grabusove, et al., ACS Nano 2024, 18 (20), 13184–13195.
