Description
Fizikālās ķīmijas un Analītiskās ķīmijas kopējā sēde
A non-intrusive multi-dimensional analysis method can be useful in many pharmaceutical applications, especially for the analysis of solid dosage forms, where spatial information using conventional analytical methods can typically only be obtained after destructive manipulations with samples prior to or during the measurements. This study demonstrated a new combination method of low-frequency...
Due to the dominating Coulombic interactions, packing of ions in ionic liquids (ILs) solely depends on ion shape and size. The free volume in ILs is thus generally smaller than in molecular liquids. The low volatility and structural tuneability of ILs make them attractive for applications involving gaseous solutes. Greater free volume can entropically contribute to absorption of gases and, for...
Selectivity is a major issue in the development of drugs targeting pathogen aspartic proteases. Here we explore the selectivity determining factors by studying specifically designed malaria aspartic protease (plasmepsin) open-flap inhibitors. 2-Aminoquinazolin-4(3H)-one based plasmepsin inhibitors with various flap pocket substituents are synthesized and their potencies against several...
Introduction. It has been shown that determination of reference intervals (RI) using accumulated general patient data can be a cost effective alternative [3] to special research following C28-A3 guidelines[1].
There are some reports on B12 RI for different ethnicities [2]. There is little and somewhat contradictory information about the B12 RI for different age groups and sexes. In this work...
